Related Studies


PASTURE/LUKAS study centres




Project - Partners

Hanover Medical School

PI: : Prof. Dr. med. Michael Kabesch
Prof. Dr. med. Michael Kabesch

Michael Kabesch is a paediatrician, paediatric pneumologist and allergologist with a specific interest in asthma and allergy genetics. In the EFRAIM Project he is leading WP 4 collaborating with the CNG and Ulm University.

Michael Kabesch studied medicine in Innsbruck, Austria, and received medical training in Munich, Germany. He was a fellow with Erika von Mutius (LMU Munich, Germany), Fernando Martinez and Donata Vercelli (Respiratory Center, Tucson, USA). 2001 he founded the research laboratory in Munich. 2009 he relocated his research group to Hannover Medical School (MHH) where he became research director for experimental allergy. Also he heads the interdisciplinary allergy center of the MHH together with Thomas Werfel.

Michael Kabesch is coordinator of asthma genetic research in the German national genome research project, steering committee member of the European consortium on asthma genetics and environment studies (GABRIEL) and PI in many projects on asthma and allergy genetics, funded by the EU, the German research council and the German Ministry for education and research. He serves on the editorial board of Allergy and is section editor for Current Opinion in Allergy and Clinical Immunology and member of the Faculty of 1000. His research was awarded with a number of national and international prices and has contributed to the current understanding of asthma and allergy as complex diseases with a strong genetic component.

Sven Michel
Sven Michel Sven Michel got his diploma in bioinformatics 2006 from the Ludwig Maximilians University and the Technical University of Munich. Since July 2007 he is a PhD student in the group '' of Prof. Dr. Kabesch working on elucidating genetic and epigenetic effects in asthma.

2008 he was rewarded with a PINA fellowship. Currently he works as a fellow on the EFRAIM project at the Centre National de Génotypage in Evry, France, under the supervision of Jörg Tost and Ivo Gut. His main focus lies on the genome wide analysis of SNP effect on promoter function, splicing variants, and their influence on asthma and allergy development. Furthermore he performs genome-wide studies on epigenetic regulation of asthma. He investigates the effects of differentially methylated DNA on the function of genes and their role in the development of asthma and atopy in children.